Name

Surname

Tomislav

Friščić

Institution name and department

McGill University, Department of Chemistry

Position held

Professor

Address/Country

Department of Chemistry, McGill University, 801 Sherbrooke St. W. H3A 0B8 Montreal, Canada

E-mail

Webpage

This email address is being protected from spambots. You need JavaScript enabled to view it.

https://friscic.research.mcgill.ca/

Key words 

Green chemistry

Metal- organic framerworks

Pharmaceuticals

Cocrystals

Organic synthesis

Mechanisms

Areas of Research/Expertise 

 My research group is generally developing new synthetic designs based on solvent- free chemistry, including mechanochemistry, ageing reactivity and thermochemistry. We are developing mechanochemistry in the context of applications (Green chemistry, pharmaceuticals, nanomaterials, metal-organic frameworks, cocrystals, metal and plastics recycling, mechano-enzymatic reactions, biomass chemicals), as well as fundamental understanding. In the context of understanding mechanochemical reactivity, we are pursuing the use and development of in situ monitoring techniques, as well as theoretical modelling approaches based on periodic density functional theory (DFT) modelling, and molecular dynamic (MD).

5 Most representative publications related to mechanochemistry

1.   Julien, P. A.; Germann, L. S.; Titi, H. M.; Etter, M.; Dinnebier, R. E.; Sharma, L.; Baltrusaitis, J.; Friščić, T. “In situ monitoring of mechanochemical synthesis of calcium urea phosphate fertilizer cocrystal reveals highly effective water-based autocatalysis“ Chem. Sci. 2020, 11, 2350-2355. https://doi.org/10.1039/C9SC06224F

2.   Friščić, T.; Mottillo, C.; Titi, H. M. “Mechanochemistry for synthesis“ Angew. Chem. Int. Ed. 2020, 59, 1018-1029. https://doi.org/10.1002/anie.201906755

3.   Kaabel, S.; Stein, R. S.; Fomitšenko, M.; Järving, I.; Friščić, T.; Aav, R. “Size-control by anion templating in mechanochemical synthesis of hemicucurbiturils in the solid state“ Angew. Chem. Int. Ed. 2019, 58, 6230-6234.  https://doi.org/10.1002/anie.201813431

4.   Hammerer, F.; Loots, L.-A.; Do, J.-L.; Therien, J. P. D.; Nickels, C. W.; Friščić, T.; Auclair, K. ”Solvent-free enzyme activity: quick, high-yielding mechano-enzymatic hydrolysis of cellulose into glucose" Angew. Chem. Int. Ed. 2018, 57, 2621-2624.  https://doi.org/10.1002/anie.201711643

5.   Friščić, T.; Halasz, I.; Beldon, P. J.; Belenguer, A. M.; Adams, F.; Kimber, S. A. J.; Honkimäki, V.; Dinnebier, R. E. "Real-time and in situ monitoring of mechanochemical reactions" Nature Chemistry, 2013, 5, 66-73. https://doi.org/10.1038/nchem.1505

5 Most representative publications non-related to Mechanochemistry 

1.   Titi, H. M.; Marrett, J. M.; Dayaker, G.; Arhangelskis, M.; Mottillo, C.; Morris, A. J.; Rachiero, G. P.; Friščić, T.; Rogers, R. D. “Hypergolic Zeolitic Imidazolate Frameworks (ZIFs) as Next-Generation Solid Fuels: Unlocking the Latent Energetic Behavior of ZIFs“ Science Adv. 2019, 5, eaav9044. DOI: 10.1126/sciadv.aav9044

2.   Lisac, K.; Topić, F.; Arhangelskis, M.; Cepić, S.; Julien, P. A.; Nickels, C. W.; Morris, A. J.; Friščić, T.; Cinčić, D. ”Halogen bonds to phosphorus, arsenic and antimony" Nature Commun. 2019, 10:61 https://doi.org/10.1038/s41467-018-07957-6

3.   Huskić, I.; Pekov, I.; Krivovichev, S.; Friščić, T. "Minerals with Metal-Organic Framework Structures" Science Adv. 2016, 2, e1600621 DOI: 10.1126/sciadv.1600621

4.   Bushuyev, O. S.; Corkery, T. C.; Barrett, C. J.; Friščić, T. "Photo-mechanical

azobenzene co-crystals and in situ X-ray diffraction study of their optically-induced crystal-to-crystal isomerization" Chem. Sci. 2014, 5, 3158-3164.  https://doi.org/10.1039/C4SC00987H

5.  Cliffe, M. J. C.; Mottillo, C.; Stein, R. S.; Bučar, D.-K.; Friščić, T. "Accelerated aging: a low energy, solvent-free alternative to solvothermal and mechanochemical synthesis of metal-organic materials" Chem. Sci. 2012, 3, 2495-2500.  https://doi.org/10.1039/C2SC20344H

Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles

Orcid ID

0000-0002-3921-7915

Google Scholar

Researchgate

Scopus profiles

Twitter/ Linkedin/ Instagram accounts

Twitter/

@TomislavFriscic

Linkedin

Instagram accounts

Primary focus in mechanochemical research (enter as bullet points)